Head-to-head for women
NewSelf vs Sesame Care
NewSelf and Sesame Care both offer GLP-1 telehealth to women, but they make different trade-offs on PCOS and hormonal suitability, clinical oversight, price and access. Here they are side-by-side on the Luna Fit Score — our women's-health rubric.
NewSelf
Ranked #54 for women · Grade C
Luna Fit
Best for: Women who are certain they want three months of a flat-priced compounded GLP-1 and will not need to change their mind, because changing it is expensive here.
Visit NewSelfSesame Care
Higher scoreRanked #4 for women · Grade B
Luna Fit
Best for: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Visit Sesame CareThe verdict for women
Sesame Care edges out NewSelf on the Luna Fit Score, 85 to 64 (B vs C). Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. The reasoning behind that number is in the Sesame Care scorecard.
NewSelf is still a genuine option — one price at any dose, three months of medication shipped up front — and a set of exit terms and unresolved compliance problems that make it the hardest program on this board to leave. Weigh the six women's-health factors below against your own priorities; our NewSelf write-up for women goes through each of them, and if neither of these two is the one, our ranked shortlist of NewSelf alternatives widens the field.
Side-by-side on the six factors
Both providers scored on the same women's-health rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | NewSelf | Sesame Care |
|---|---|---|
| Luna Fit Score | 64/100 · C | 85/100 · B |
| Overall rank | #54 | #4 |
| Semaglutide | $134.99/mo flat at every dose (as low as $99.97; 3-month term required) | From $149/mo (brand Wegovy pill) |
| Tirzepatide | $224.99/mo flat at every dose (as low as $144.49; 3-month term required) | Brand Zepbound (price varies) |
| Coverage | 48 states and Puerto Rico (not Mississippi or Louisiana) | Nationwide marketplace |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Luna Fit
NewSelf
Ranked #54 · Grade C
What we like
- One flat price at every dose for both molecules, with the dose ladder published beside it
- Three months of medication shipped up front, so there is no waiting on refills mid-titration
- LegitScript certified with a published, checkable ID
The caveats
- FDA warning letter MARCS-CMS 721472, dated 20 February 2026, to NewSelf Limited dba NewSelf, over product labelling and marketing language. As of 1 August 2026 the wording the FDA objected to was still live on the site — five months on, unremediated
- The product pages carry a badge reading 'cancel anytime', while the refund policy requires a three-month commitment and charges a full retail month as an early-cancellation fee. Those cannot both be true
- No refunds: cancelling before the doctor's review costs a $99 administrative fee, and after it nothing is refundable regardless of shipment status
Luna Fit
Sesame Care
Ranked #4 · Grade B
What we like
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
The caveats
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. Pricing, states and verification reflect each provider's public disclosures at last review; the Luna Fit Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Neither NewSelf nor Sesame Care is only worth comparing with the other. NewSelf is also written up against CoreAge Rx, 29 points apart on the Luna Fit Score — see the NewSelf–CoreAge Rx head-to-head. Sesame Care is also written up against CoreAge Rx, 8 points apart — see Sesame Care against CoreAge Rx, factor by factor.
- NewSelf vs CoreAge Rx
- NewSelf vs Enhance MD
- NewSelf vs yourEra
- Sesame Care vs HealthRX
- Sesame Care vs Strut Health
- Sesame Care vs MadeMed
Or browse the full comparison hub.